Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661514 | 0.67 | CA2 (0.36) | CA1CA2CA9CA7CA13 | |
| SCHEMBL276235 | 0.64 | TSHR (0.32) | CA1CA2CA7 | |
| SCHEMBL16453575 | 0.62 | — | — | |
| SCHEMBL28479454 | 0.60 | CA2 (0.39) | CA1CA2CA9CA7 | |
| SCHEMBL28487463 | 0.60 | CA2 (0.39) | CA1CA2CA9CA7 | |
| SCHEMBL28479453 | 0.60 | CA2 (0.39) | CA1CA2CA9CA7 | |
| SCHEMBL240329 | 0.59 | — | — | |
| SCHEMBL22089786 | 0.59 | — | — | |
| SCHEMBL1751437 | 0.59 | — | — | |
| SCHEMBL23670047 | 0.58 | CA2 (0.32) | CA1CA2CA9CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512953-B1 | Process for the preparation of benzene sulfonamides | CIBA GEIGY AG (CH) | 1995-06-07 | — | — | EP | claimed |
| US-5220062-A | PROCESS FOR THE PREPARATION OF BENEZENESULFONAMIDES | CIBA-GEIGY CORPORATION (US) | 1993-06-15 | — | — | US | claimed |
| EP-0512953-A1 | Process for the preparation of benzene sulfonamides | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | claimed |
| EP-0512953-B1 | Process for the preparation of benzene sulfonamides | CIBA GEIGY AG (CH) | 1995-06-07 | — | — | EP | disclosed |
| US-5220062-A | PROCESS FOR THE PREPARATION OF BENEZENESULFONAMIDES | CIBA-GEIGY CORPORATION (US) | 1993-06-15 | — | — | US | disclosed |
| EP-0512953-A1 | Process for the preparation of benzene sulfonamides | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | disclosed |