Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylmalonate SCHEMBL107241 | 0.96 | — | — | |
| Ethylmalonate SCHEMBL9765245 | 0.93 | HDAC1 (0.43) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| Ethylmalonate SCHEMBL29018396 | 0.93 | HDAC1 (0.43) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| Ethylmalonate SCHEMBL27701081 | 0.93 | HDAC1 (0.43) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| Ethylmalonate SCHEMBL83437 | 0.93 | HDAC1 (0.43) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| Ethylmalonate SCHEMBL108554 | 0.93 | HDAC1 (0.43) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| Ethylmalonate SCHEMBL108039 | 0.93 | HDAC1 (0.43) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| Ethylmalonate SCHEMBL9118935 | 0.93 | HDAC1 (0.43) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| Ethylmalonate SCHEMBL3157979 | 0.93 | HDAC1 (0.43) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| Ethylmalonate SCHEMBL28314280 | 0.93 | HDAC1 (0.43) | HDAC1HDAC2CHRM1AKR1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110172019-A | The metal salt of malonic acid as the nucleating additive for crystalline thermoplastic | 印度石油有限公司 | 2019-08-27 | — | — | CN | claimed |
| EP-4631955-A1 | PURIFICATION METHOD AND PRODUCTION METHOD OF CYCLIC PEPTIDE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024143514-A1 | PURIFICATION METHOD AND PRODUCTION METHOD OF CYCLIC PEPTIDE | 中外製薬株式会社 | 2024-07-04 | — | — | WO | disclosed |
| CN-116854744-A | Synthesis and application of chiral spiro [ chromane-4, 1' -indan ] bidentate ligand iridium complex | 南开大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-116655691-A | Synthesis and application of chiral spiro [ chromane-4, 1' -indan ] phosphite monophosphorus ligand | 南开大学 | 2023-08-29 | — | — | CN | disclosed |
| US-11572384-B2 | Unusual substrates of tubulin tyrosine ligase | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2023-02-07 | — | — | US | disclosed |
| US-11279733-B2 | Peptide antibiotics | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-03-22 | — | — | US | disclosed |
| CN-110172019-B | Metal salts of malonic acid as nucleating additives for crystalline thermoplastics | 印度石油有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-109970697-B | Synthesis method of chiral spiro [ chroman-4, 1' -indan ] molecule | 南开大学 | 2021-10-12 | — | — | CN | disclosed |
| US-20200361994-A1 | PEPTIDE ANTIBIOTICS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-11-19 | — | — | US | disclosed |
| US-6331548-B1 | PREVENTION OR TREATMENT OF CYTOKINE RELATED DISEASES | SUNTORY LIMITED (JP) | 2001-12-18 | — | — | US | disclosed |
| CN-1268947-A | Novel process for preparing 4-hydroxy-2-oxo-pyran derivatives as protease inhibitors | UPJOHN CO (US) | 2000-10-04 | — | — | CN | disclosed |
| EP-0990654-A1 | SUBSTITUTED CYCLOBUTYLAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |
| EP-0978516-A1 | 1-CYCLOALKYL-1,8-NAPHTHYRIDIN-4-ONE DERIVATIVES WITH PHOSPHODIESTERASE IV INHIBITORY ACTIVITY | SUNTORY LIMITED (JP) | 2000-02-09 | — | — | EP | disclosed |
| CN-1049219-C | Fused heteroaromatic cyclopentene derivative having endothelin-antagonist activity | BANYU PHARMA CO LTD (JP) | 2000-02-09 | — | — | CN | disclosed |
| US-5948786-A | BLOCKING TUMOR NECROSIS FACTOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0892795-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997038992-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-23 | — | — | WO | disclosed |
| CN-1129448-A | Fused heteroaromatic cyclopentene derivative having endothelin-antagonist activity | BANYU PHARMA CO LTD (JP) | 1996-08-21 | — | — | CN | disclosed |
| CN-1095718-A | Condensed heterocycle compound, their preparation and purposes | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-11-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572384-B2 | Unusual substrates of tubulin tyrosine ligase | TTL, TUBA1C, TUBB6 | HDAC1 3887/4885HDAC2 4483/4885CHRM1 4792/4885 |
| US-20200361994-A1 | PEPTIDE ANTIBIOTICS | NGLY1, VIP, PEPD | HDAC1 3213/4885HDAC2 3989/4885CHRM1 4873/4885 |
| US-11279733-B2 | Peptide antibiotics | NGLY1, VIP, PEPD | HDAC1 3213/4885HDAC2 3989/4885CHRM1 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.