Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.47 |
| ▸ | RARB | P10826 | 6/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9122860 | 0.99 | AGTR1 (0.47) | AGTR1AGTR2RARBTLR7TLR8 | |
| SCHEMBL9654571 | 0.85 | AGTR1 (0.56) | AGTR1AGTR2DHODH | |
| SCHEMBL8504803 | 0.82 | DHODH (0.51) | AGTR1AGTR2DHODH | |
| SCHEMBL8504676 | 0.81 | NR1H4 (0.49) | AGTR1AGTR2RARBTLR7DHODH | |
| SCHEMBL9120742 | 0.80 | RARB (0.46) | AGTR1AGTR2RARBTLR7 | |
| SCHEMBL9118013 | 0.80 | AGTR1 (0.47) | AGTR1AGTR2RARBTLR7TLR8 | |
| SCHEMBL8780493 | 0.80 | TLR8 (0.42) | TLR7TLR8ALDH1A1KMT2A | |
| SCHEMBL8584304 | 0.78 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9119822 | 0.77 | RARB (0.43) | AGTR1AGTR2RARBTLR7 | |
| SCHEMBL9119796 | 0.75 | DHODH (0.53) | AGTR1AGTR2RARBTLR7DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478938-A | Antagonists for angiotensin II receptors; hypotensive, cardiotonic agents; cognitive activators | ROUSSEL UCLAF (FR) | 1995-12-26 | — | — | US | claimed |