Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | MPL | P40238 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058443 | 0.87 | ADAM17 (0.54) | KDM4EAGTR1AGTR2TSHRADAM17 | |
| SCHEMBL7834869 | 0.85 | DHODH (0.59) | DHODHAGTR1AGTR2 | |
| SCHEMBL9119211 | 0.82 | RARB (0.47) | DHODHKDM4EAGTR1AGTR2TLR7 | |
| SCHEMBL7838473 | 0.81 | NR1H4 (0.49) | DHODHKDM4EAGTR1AGTR2TLR7 | |
| Hydrochloric Acid SCHEMBL8502040 | 0.81 | NR1H4 (0.48) | DHODHKDM4EAGTR1AGTR2TLR7 | |
| SCHEMBL7849445 | 0.81 | DHODH (0.51) | DHODHKDM4EAGTR1AGTR2TLR7 | |
| SCHEMBL8780501 | 0.81 | MEN1 (0.42) | DHODHKDM4ETLR7TSHR | |
| SCHEMBL8673292 | 0.80 | KDM4E (0.55) | DHODHKDM4ETSHR | |
| SCHEMBL7834873 | 0.80 | DHODH (0.47) | DHODHKDM4EAGTR1AGTR2 | |
| SCHEMBL8501790 | 0.80 | PLA2G2A (0.52) | DHODHAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478938-A | Antagonists for angiotensin II receptors; hypotensive, cardiotonic agents; cognitive activators | ROUSSEL UCLAF (FR) | 1995-12-26 | — | — | US | disclosed |
| US-5324839-A | Hypotensive agents, gastrointestinal and urogenital disorders | ROUSSEL-UCLAF (FR) | 1994-06-28 | — | — | US | disclosed |