Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.62 |
| ▸ | AHR | P35869 | 1/20 | 0.60 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | IKBKB | O14920 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 2/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146560 | 0.81 | TSHR (0.63) | TSHRHAVCR2G6PDCASP7CASP6 | |
| Acetic Acid SCHEMBL27461652 | 0.80 | AHR (0.75) | KEAP1AHRPDPK1GRM5ALDH1A1 | |
| SCHEMBL9119040 | 0.78 | G6PD (0.65) | KEAP1AHRPDPK1GRM5G6PD | |
| SCHEMBL29696550 | 0.78 | KEAP1 (1.00) | KEAP1AHRPDPK1GRM5ALDH1A1 | |
| SCHEMBL336234 | 0.78 | KEAP1 (1.00) | KEAP1AHRPDPK1GRM5ALDH1A1 | |
| SCHEMBL443938 | 0.78 | AHR (1.00) | KEAP1AHRPDPK1GRM5IKBKB | |
| SCHEMBL9117203 | 0.77 | KEAP1 (0.62) | KEAP1PDPK1GRM5G6PDCASP7 | |
| Hydrochloric Acid SCHEMBL8595147 | 0.76 | KEAP1 (0.96) | KEAP1AHRPDPK1GRM5ALDH1A1 | |
| Formic Acid SCHEMBL28403706 | 0.75 | AHR (0.78) | KEAP1AHRPDPK1GRM5ALDH1A1 | |
| SCHEMBL9117851 | 0.74 | KEAP1 (0.57) | KEAP1PDPK1TSHRG6PDCASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995034658-A1 | MICROBIAL PRODUCTION OF INDOLE-3-ACETIC ACIDS AND SUBSTITUTED ANALOGS THEREOF VIA FERMENTATION | GENENCOR INTERNATIONAL, INC. (US) | 1995-12-21 | — | — | WO | disclosed |