Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125210 | 0.88 | ALDH1A1 (0.54) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL9123564 | 0.87 | ALDH1A1 (0.53) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL9123800 | 0.86 | ALDH1A1 (0.55) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL9121775 | 0.86 | ALDH1A1 (0.52) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL9121387 | 0.86 | RECQL (0.52) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL9292125 | 0.85 | ALDH1A1 (0.49) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL10624673 | 0.84 | ALDH1A1 (0.65) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL9124141 | 0.84 | ALDH1A1 (0.47) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL9121463 | 0.81 | ALDH1A1 (0.52) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL3768538 | 0.81 | ALDH1A1 (0.51) | ALDH1A1RECQLMAPK1PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395827-A | Analgesic, anticonvulsant, antiepileptic and anxiolytic agents | GUILFORD PHARMACEUTICALS INC. (US) | 1995-03-07 | — | — | US | disclosed |
| US-5364876-A | Tranquilizers, analgesics, learning enhancement | GUILFORD PHARMACEUTICALS INC. (US) | 1994-11-15 | — | — | US | disclosed |
| WO-1993005772-A1 | φ-[2-(PHOSPHONOALKYL)PHENYL]-2-AMINOALKANOIC ACIDS AS ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS | NOVA PHARMACEUTICAL CORPORATION (US) | 1993-04-01 | — | — | WO | disclosed |