Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 8/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14392329 | 1.00 | MMP8 (0.56) | MMP8SRRPIN1PPARGPPARA | |
| SCHEMBL3541115 | 0.86 | MMP8 (0.56) | MMP8SRRPIN1PPARGPPARA | |
| SCHEMBL27546630 | 0.86 | MMP8 (0.56) | MMP8SRRPIN1PPARGPPARA | |
| SCHEMBL7150900 | 0.86 | SRR (0.56) | SRRPPARGPPARAALDH1A1PPARD | |
| SCHEMBL3694538 | 0.85 | ESR1 (0.51) | MMP8PPARA | |
| SCHEMBL5360147 | 0.85 | ESR1 (0.51) | MMP8PPARA | |
| SCHEMBL14392121 | 0.85 | PPARA (0.45) | MMP8SRRPIN1PPARGPPARA | |
| SCHEMBL27798684 | 0.84 | MMP8 (0.51) | MMP8SRRPIN1PPARGPPARA | |
| SCHEMBL11436318 | 0.83 | MMP8 (0.54) | MMP8SRRPIN1PPARGPPARA | |
| SCHEMBL6632835 | 0.83 | SMN1; SMN2 (0.54) | MMP8PIN1PPARGPPARAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269341-A | Catalyst for synthesizing high isotactic polybutene and its prepn | 青岛科技大学 | 2020-06-12 | — | — | CN | disclosed |
| CN-1230175-A | Cytostatic hydroximic acid derivatives | BRITISH BIOTECH PHARM (GB) | 1999-09-29 | — | — | CN | disclosed |
| US-5434186-A | Antiinflammatory agents | HOFFMANN-LA ROCHE INC. (US) | 1995-07-18 | — | — | US | disclosed |
| US-5273999-A | A 4-keto-boroalkyleneoxychroman or 2,3-dihydrobenzofuran derivative | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0531823-A1 | Bicyclic carboxylic acid derivatives as anti-inflammatory agents | F. HOFFMANN-LA ROCHE AG (CH) | 1993-03-17 | — | — | EP | disclosed |