SCHEMBL9119491

SCHEMBL9119491

CC(C)(C)c1nc2c(Cl)ccc(-c3onc(C=O)c3C3CC3)c2o1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMURF2 Q9HAU4 1/20 0.30
SMURF1 Q9HCE7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9118907 0.71 NPC1 (0.30)
SCHEMBL9119496 0.67
SCHEMBL6200595 0.66 DHODH (0.34)
SCHEMBL6182747 0.61 RARA (0.36)
SCHEMBL7470660 0.61 ELANE (0.35)
Hydrochloric Acid SCHEMBL7470667 0.60 RARA (0.35)
SCHEMBL7475979 0.60 MEN1 (0.35)
SCHEMBL6185269 0.59 KDM4E (0.38)
SCHEMBL22675657 0.55 ELANE (0.37)
SCHEMBL17293387 0.54 CXCR2 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995025105-A1 ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES RHONE-POULENC AGRICULTURE LTD (GB) 1995-09-21 WO claimed
WO-1995025105-A1 ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES RHONE-POULENC AGRICULTURE LTD (GB) 1995-09-21 WO disclosed