⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9472193 | 0.80 | HPGD (0.35) | — | |
| SCHEMBL9121110 | 0.77 | KDM4E (0.33) | — | |
| SCHEMBL8872265 | 0.74 | KDM4E (0.39) | — | |
| SCHEMBL9123097 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL8871659 | 0.70 | — | — | |
| SCHEMBL9120540 | 0.69 | — | — | |
| SCHEMBL9120983 | 0.67 | L3MBTL1 (0.31) | — | |
| SCHEMBL9399193 | 0.66 | — | — | |
| SCHEMBL8872326 | 0.66 | KDM4E (0.42) | — | |
| Acetic Acid SCHEMBL9244244 | 0.66 | GAA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372263-B1 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID CO (US) | 1995-02-15 | — | — | EP | claimed |
| EP-0557732-A1 | Methods and compositions for protecting animals against attack and infestation by helminth, acarid and anthropod endo- and ectoparasites | AMERICAN CYANAMID COMPANY (US) | 1993-09-01 | — | — | EP | claimed |
| US-5162308-A | Pyrrole carbonitrile and nitropyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1992-11-10 | — | — | US | claimed |
| EP-0372263-A2 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1990-06-13 | — | — | EP | claimed |
| EP-0557732-A1 | Methods and compositions for protecting animals against attack and infestation by helminth, acarid and anthropod endo- and ectoparasites | AMERICAN CYANAMID COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |