Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.56 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.56 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2069778 | 0.89 | MAPT (0.69) | POLBKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11086324 | 0.86 | KMT2A (0.76) | POLBKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1815770 | 0.86 | PKM (0.65) | POLBKMT2AMEN1ALDH1A1PDK1 | |
| SCHEMBL9123407 | 0.84 | ALDH1A1 (0.64) | POLBKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11811441 | 0.84 | POLB (0.63) | POLBKMT2AMEN1ALDH1A1PDK1 | |
| SCHEMBL2070549 | 0.83 | MAPT (0.70) | POLBKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11810837 | 0.83 | POLB (0.61) | POLBKMT2AMEN1ALDH1A1PDK1 | |
| SCHEMBL10489728 | 0.83 | SMN1; SMN2 (0.65) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2070357 | 0.82 | KMT2A (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11159531 | 0.82 | MAPT (0.62) | KMT2AALDH1A1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496595-B1 | Aniline derivatives and process for producing the same | NISSAN CHEMICAL IND LTD (JP) | 1995-09-06 | — | — | EP | disclosed |
| US-5416236-A | Sulfonylation, reduction and carbamylation in multistage process | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0496595-A1 | Aniline derivatives and process for producing the same | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1992-07-29 | — | — | EP | disclosed |