Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119627 | 0.93 | GRIK1 (0.52) | RXFP1GRIK1IDO1MAPTTDP1 | |
| SCHEMBL5595139 | 0.86 | CCR1 (0.54) | GRIK1IDO1MAPTLMNANPSR1 | |
| SCHEMBL9118380 | 0.85 | GRIK1 (0.47) | RXFP1GRIK1MAPTLMNANPSR1 | |
| SCHEMBL9185640 | 0.84 | IDO1 (0.47) | GRIK1IDO1MAPTLMNANPSR1 | |
| SCHEMBL9117124 | 0.83 | GRIK1 (0.58) | RXFP1GRIK1MAPTTDP1KDR | |
| SCHEMBL9117108 | 0.81 | GRIK1 (0.47) | GRIK1IDO1MAPTTDP1TAS2R14 | |
| Diphenylmethanol SCHEMBL9117115 | 0.81 | CCR1 (0.49) | GRIK1IDO1MAPTLMNANPSR1 | |
| Diphenylmethanol SCHEMBL9185659 | 0.81 | CCR1 (0.49) | GRIK1IDO1MAPTLMNANPSR1 | |
| SCHEMBL9118124 | 0.80 | GRIK1 (0.61) | RXFP1GRIK1MAPTKDRMEN1 | |
| SCHEMBL9117381 | 0.75 | PTGES (0.52) | GRIK1P2RY1MAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033460-A1 | ANTI-INFLAMMATORY COUMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |