Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.93 |
| ▸ | PPARD | Q03181 | 3/20 | 0.78 |
| ▸ | FABP2 | P12104 | 2/20 | 0.78 |
| ▸ | PPARG | P37231 | 2/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558046 | 1.00 | PPARA (0.93) | PPARAPPARDFABP2PPARGSMN1; SMN2 | |
| SCHEMBL1304938 | 0.89 | PPARA (0.74) | PPARAPPARDFABP2PPARGSMN1; SMN2 | |
| SCHEMBL3690900 | 0.88 | PPARA (0.74) | PPARAPPARDFABP2PPARGSMN1; SMN2 | |
| SCHEMBL9119026 | 0.88 | PPARA (0.74) | PPARAPPARDFABP2PPARGSMN1; SMN2 | |
| SCHEMBL8269751 | 0.88 | PPARA (0.73) | PPARAPPARDFABP2PPARGSMN1; SMN2 | |
| Bezafibrate SCHEMBL5077755 | 0.88 | PPARA (1.00) | PPARAPPARDFABP2PPARGSMN1; SMN2 | |
| Bezafibrate SCHEMBL16299 | 0.88 | PPARA (1.00) | PPARAPPARDFABP2PPARGSMN1; SMN2 | |
| Bezafibrate SCHEMBL3088387 | 0.86 | PPARA (0.98) | PPARAPPARDFABP2PPARGSMN1; SMN2 | |
| Bezafibrate SCHEMBL22364278 | 0.86 | PPARA (0.98) | PPARAPPARDFABP2PPARGSMN1; SMN2 | |
| SCHEMBL9120807 | 0.86 | PPARA (0.71) | PPARAPPARDFABP2PPARGSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382680-A | Allosteric hemoglobin modifier compounds | THE CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1995-01-17 | — | — | US | disclosed |