Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119701 | 1.00 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL2290699 | 0.83 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL646616 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL646614 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL9440500 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL9440511 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL647484 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL647486 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL6675229 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL6675232 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350314-B1 | Silicone type cinnamic acid derivative, preparation method thereof, uv-ray absorber, and external skin treatment agent. | SHISEIDO CO LTD (JP) | 1995-12-13 | — | — | EP | disclosed |
| US-5093511-A | SILICONE TYPE CINNAMIC ACID DERIVATIVE, PREPARATION METHOD THEREOF, UV-RAY ABSORBER, AND EXTERNAL SKIN TREATMENT AGENT | SHISEIDO COMPANY, LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0350314-A2 | Silicone type cinnamic acid derivative, preparation method thereof, uv-ray absorber, and external skin treatment agent. | SHISEIDO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |