Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119854 | 1.00 | KDM4E (0.43) | KDM4EABCG2CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL647361 | 0.88 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL647363 | 0.88 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL646206 | 0.81 | KDM4E (0.48) | KDM4EABCG2CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL646208 | 0.81 | KDM4E (0.48) | KDM4EABCG2CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL645499 | 0.73 | KDM4E (0.41) | KDM4EPTGER4PTGER2PTGER3ALDH1A1 | |
| SCHEMBL645501 | 0.73 | KDM4E (0.41) | KDM4EPTGER4PTGER2PTGER3ALDH1A1 | |
| SCHEMBL9440557 | 0.73 | KDM4E (0.41) | KDM4EPTGER4PTGER2PTGER3ALDH1A1 | |
| SCHEMBL9440571 | 0.73 | KDM4E (0.41) | KDM4EPTGER4PTGER2PTGER3ALDH1A1 | |
| SCHEMBL6675232 | 0.71 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350314-B1 | Silicone type cinnamic acid derivative, preparation method thereof, uv-ray absorber, and external skin treatment agent. | SHISEIDO CO LTD (JP) | 1995-12-13 | — | — | EP | disclosed |
| US-5315022-A | Sunscreen | SHISEIDO COMPANY LTD. (JP) | 1994-05-24 | — | — | US | disclosed |
| US-5093511-A | SILICONE TYPE CINNAMIC ACID DERIVATIVE, PREPARATION METHOD THEREOF, UV-RAY ABSORBER, AND EXTERNAL SKIN TREATMENT AGENT | SHISEIDO COMPANY, LTD. (JP) | 1992-03-03 | — | — | US | disclosed |