Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 2/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | CPA3 | P15088 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863960 | 0.80 | ALDH1A1 (0.49) | NPC1RAB9A | |
| SCHEMBL8403391 | 0.80 | CYP1A2 (0.47) | CYP1A2CPA1CPB1CPA3CPB2 | |
| SCHEMBL17931631 | 0.79 | MAOB (0.74) | MAOBADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL10441970 | 0.79 | MAOB (0.74) | MAOBADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL27886896 | 0.79 | SLC6A2 (0.61) | MAOBADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL547492 | 0.79 | ALDH1A1 (0.43) | — | |
| SCHEMBL8430263 | 0.78 | SIGMAR1 (0.50) | MAOBADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL547805 | 0.77 | SMN1; SMN2 (0.42) | ADRA2BHTR2AKCNH2 | |
| SCHEMBL23422467 | 0.75 | ALDH1A1 (0.40) | MAOB | |
| SCHEMBL31545352 | 0.74 | SLC6A2 (0.60) | MAOBADRA2BADRA2CSLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995029903-A1 | STEREOPREFERENTIAL SYNTHESIS OF 3-(1-PHENYLPROP-2-YL)-5-PHENYLOXAZOLIDINONES | CELGENE CORPORATION (US) | 1995-11-09 | — | — | WO | disclosed |