SCHEMBL9121967

SCHEMBL9121967

CCCCOC(=O)N=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6576430 0.83 ALDH1A1 (0.58)
SCHEMBL158105 0.83 ALDH1A1 (0.58)
SCHEMBL843522 0.83 ALDH1A1 (0.58)
SCHEMBL968305 0.81
SCHEMBL15843351 0.79 ALDH1A1 (0.54)
SCHEMBL15843513 0.79 ALDH1A1 (0.54)
SCHEMBL15843352 0.79 ALDH1A1 (0.54)
SCHEMBL15843512 0.79 ALDH1A1 (0.54)
SCHEMBL970929 0.79 ALDH1A1 (0.54)
SCHEMBL8057564 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5462956-A Potency; not blocked by opioid-antagonist naloxone THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1995-10-31 US disclosed
EP-0629200-A1 EPIBATIDINE AND DERIVATIVES, COMPOSITIONS AND METHODS OF TREATING PAIN THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1994-12-21 EP disclosed
US-5314899-A Epibatidine and derivatives, compositions and methods of treating pain THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1994-05-24 US disclosed
WO-1993018037-A1 EPIBATIDINE AND DERIVATIVES, COMPOSITIONS AND METHODS OF TREATING PAIN THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1993-09-16 WO disclosed