SCHEMBL843522

SCHEMBL843522

CCCCOC(=O)N=NC(=O)OCCCC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.58
ATM Q13315 1/20 0.54
TSHR P16473 5/20 0.50
HPGD P15428 1/20 0.50
HCAR2 Q8TDS4 1/20 0.47
NAAA Q02083 1/20 0.46
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
EPHX1 P07099 1/20 0.43
ESR1 P03372 2/20 0.42
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPK1 P28482 1/20 0.42
CYP2C19 P33261 1/20 0.42
NR1H2 P55055 1/20 0.42
RNASEL Q05823 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ACHE P22303 6/20 0.42
DGKA P23743 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL158105 1.00 ALDH1A1 (0.58) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL15843351 0.95 ALDH1A1 (0.54) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL15843352 0.95 ALDH1A1 (0.54) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL15843513 0.95 ALDH1A1 (0.54) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL15843512 0.95 ALDH1A1 (0.54) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL15843050 0.93 NAAA (0.57) ALDH1A1ATMTSHRHCAR2NAAA
SCHEMBL15843109 0.93 NAAA (0.57) ALDH1A1ATMTSHRHCAR2NAAA
SCHEMBL15843409 0.93 NAAA (0.57) ALDH1A1ATMTSHRHCAR2NAAA
SCHEMBL15843731 0.93 ALDH1A1 (0.52) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL15843110 0.93 NAAA (0.57) ALDH1A1ATMTSHRHCAR2NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250051302-A1 Method for Preparation of (2R,3S)-2-(benzo[d]imidazolylpropyl)piperidin-3-ol Derivatives DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2025-02-13 US claimed
WO-2023113534-A1 METHOD FOR PREPARATION OF (2R, 3S)-2-(BENZO[D]IMIDAZOLYLPROPYL)PIPERIDIN-3-OL DERIVATIVES 주식회사 대웅제약 2023-06-22 WO claimed
CN-110294709-B 1,3- [2H,4H ] -isoquinoline dione derivative and preparation method and application thereof 贵州医科大学 2021-06-29 CN claimed
US-9315599-B2 Functionalized polymers BRIDGESTONE CORPORATION (JP) 2016-04-19 US claimed
WO-2014107447-A1 FUNCTIONALIZED POLYMERS BRIDGESTONE CORPORATION (JP) 2014-07-10 WO claimed
US-20140187712-A1 FUNCTIONALIZED POLYMERS BRIDGESTONE CORPORATION (JP) 2014-07-03 US claimed
JP-3043813-B2 2000-05-22 JP claimed
US-6051711-A ACID HYDROLYSIS IN THE PRESENCE OF A C1-C4 ALKANOL TO OBTAIN A CRYSTALLINE SALT OF SWAINSONINE GLYCODESIGN INC. (CA) 2000-04-18 US claimed
US-5874577-A Method for the preparing 9-12-(Diethoxyphosphonomethoxy)ethyl!adenine and analogues thereof MEDICHEM RESEARCH, INC. (US) 1999-02-23 US claimed
US-5847164-A Method for the preparation of chromanone 7 SARAWAK MEDICHEM PHARMACEUTICALS, INC. (US) 1998-12-08 US claimed
EP-0775130-A1 METHOD FOR THE PREPARATION OF (+/-)-CALANOLIDE A AND INTERMEDIATES THEREOF MEDICHEM RESEARCH, INC. (US) 1997-05-28 EP claimed
WO-1996004263-A1 METHOD FOR THE PREPARATION OF (±)-CALANOLIDE A AND INTERMEDIATES THEREOF MEDICHEM RESEARCH, INC. (US) 1996-02-15 WO claimed
US-20250051302-A1 Method for Preparation of (2R,3S)-2-(benzo[d]imidazolylpropyl)piperidin-3-ol Derivatives DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2025-02-13 US disclosed
US-20250011326-A1 FUSED HETEROCYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OF HBV INFECTION Janssen Sciences Ireland Unlimited Company (IE) 2025-01-09 US disclosed
EP-3868766-B1 PHOTOLUMINESCENT GREASE COMPOSITION, PHOTOLUMINESCENT MATERIAL AND PREPARATION METHOD THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2024-05-08 EP disclosed
US-11898118-B2 Photoluminescent lubricating grease composition, photoluminescent material and the preparation methods thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2024-02-13 US disclosed
US-5331075-A Blend of polysiloxanes, one containing vinyl group and the other a silicon hydride group GENERAL ELECTRIC COMPANY (US) 1994-07-19 US disclosed
EP-0581618-A1 Rubber composition and production thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-02-02 EP disclosed
EP-0545591-A1 Heat curable organopolysiloxane compositions and preformed latent platinum catalysts GENERAL ELECTRIC COMPANY (US) 1993-06-09 EP disclosed
US-5055545-A Paint primers; bonding strength; tire sidewalls; decoration BRIDGESTONE/FIRESTONE, INC. (US) 1991-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11898118-B2 Photoluminescent lubricating grease composition, photoluminescent material and the preparation methods thereof TPSD1, TPSG1, TPSB2 ALDH1A1 793/4885ATM 789/4885TSHR 3802/4885
US-20250011326-A1 FUSED HETEROCYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OF HBV INFECTION HAVCR2, HCCS, HDGF ALDH1A1 3167/4885ATM 3579/4885TSHR 3425/4885
US-20250051302-A1 Method for Preparation of (2R,3S)-2-(benzo[d]imidazolylpropyl)piperidin-3-ol Derivatives PIR, CBR3, UBE2D3 ALDH1A1 721/4885ATM 3970/4885TSHR 3404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.