Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9284059 | 0.93 | TSHR (0.52) | TSHRCYP3A4MAPTHTTMEN1 | |
| Hexane SCHEMBL515233 | 0.87 | OPRM1 (0.42) | TSHRHTTMEN1THRBKMT2A | |
| Ether SCHEMBL11182899 | 0.84 | TSHR (0.60) | TSHRCYP3A4MAPTHTTMEN1 | |
| Ether SCHEMBL2530474 | 0.84 | TSHR (0.60) | TSHRCYP3A4MAPTHTTMEN1 | |
| Ether SCHEMBL28331776 | 0.84 | TSHR (0.34) | TSHRCYP3A4MAPTHTTHSD17B10 | |
| Butoxyethanol SCHEMBL28059742 | 0.82 | TSHR (0.74) | TSHRCYP3A4MAPTHTTMEN1 | |
| Ether SCHEMBL351284 | 0.82 | TSHR (0.57) | TSHRCYP3A4MAPTHTTMEN1 | |
| Ether SCHEMBL9793363 | 0.82 | LMNA (0.37) | THRB | |
| Ether SCHEMBL437946 | 0.82 | LMNA (0.37) | THRB | |
| SCHEMBL28879226 | 0.80 | TSHR (0.71) | TSHRCYP3A4MAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422226-A | Compact disk having cured print layer on protective layer covering recording layer; heat resistance; non-delaminating | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-06-06 | — | — | US | disclosed |