Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9127603 | 0.88 | RAB9A (0.53) | ALDH1A1RAB9ANPC1CYP1A2CYP2C9 | |
| SCHEMBL9124116 | 0.86 | GSK3B (0.48) | ALDH1A1POLBHPGDHSD17B10LMNA | |
| SCHEMBL9125866 | 0.86 | SMN1; SMN2 (0.41) | TNIKALDH1A1RAB9ANPC1CYP1A2 | |
| SCHEMBL9124047 | 0.86 | MAPK1 (0.49) | ALDH1A1POLBRAB9ANPC1CYP1A2 | |
| SCHEMBL9125517 | 0.86 | RAB9A (0.48) | ALDH1A1RAB9ANPC1CYP1A2CYP2C9 | |
| SCHEMBL9126080 | 0.86 | RAB9A (0.48) | ALDH1A1RAB9ANPC1CYP1A2CYP2C9 | |
| SCHEMBL9124436 | 0.84 | RAB9A (0.41) | TNIKALDH1A1RAB9ANPC1CYP1A2 | |
| SCHEMBL9126984 | 0.84 | MGLL (0.57) | ALDH1A1POLBRAB9ANPC1MAPT | |
| SCHEMBL9126391 | 0.83 | TNIK (0.49) | TNIKALDH1A1POLBRAB9ANPC1 | |
| SCHEMBL9126424 | 0.80 | BRD4 (0.43) | ALDH1A1POLBRAB9ANPC1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524419-B1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS (JP) | 1995-09-06 | — | — | EP | disclosed |
| US-5391806-A | A storage stable chromogens as color-developing agent or stabilizers | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5270281-A | Chromogenic compound | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0524419-A1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-27 | — | — | EP | disclosed |