Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14867347 | 0.78 | GRM4 (0.76) | GRM4MAPTMEN1KMT2ANPC1 | |
| SCHEMBL6923559 | 0.77 | GRM4 (1.00) | GRM4LMNAKDRAURKBABCG2 | |
| SCHEMBL9138367 | 0.70 | GRM4 (0.46) | GRM4MAPTALDH1A1HTTLMNA | |
| SCHEMBL14430215 | 0.68 | GRM4 (0.43) | GRM4MAPTALDH1A1HTTLMNA | |
| SCHEMBL4498501 | 0.65 | AURKA (0.63) | GAAMAPTALDH1A1HTTLMNA | |
| SCHEMBL9702768 | 0.65 | HDAC6 (0.65) | GAAMAPTALDH1A1HTTLMNA | |
| SCHEMBL23067956 | 0.64 | GRM4 (0.41) | GRM4MAPTALDH1A1HTTLMNA | |
| SCHEMBL5027038 | 0.64 | CA12 (0.62) | GAAMAPTALDH1A1HTTLMNA | |
| SCHEMBL15064423 | 0.63 | NAMPT (0.53) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL21933041 | 0.63 | GAA (0.50) | GAAMAPTALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391482-A | Method and diagnostic agent for enzyme substrate stabilization using 1-arylsemicarbazides | BOEHRINGER MANNHEIM GMBH (DE) | 1995-02-21 | — | — | US | claimed |
| US-5334505-A | For colorimetric determination of hydrolases | BOEHRINGER MANNHEIM GMBH (DE) | 1994-08-02 | — | — | US | claimed |