Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | COMT | P21964 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341142 | 0.84 | SLC40A1 (0.62) | HDAC6ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL22926774 | 0.83 | HDAC6 (0.61) | HDAC6ALDH1A1GAAMAPTMEN1 | |
| SCHEMBL24522570 | 0.83 | MAPT (0.67) | HDAC6ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3352386 | 0.82 | HDAC6 (0.59) | HDAC6ALDH1A1GAAMAPTMEN1 | |
| SCHEMBL1144237 | 0.82 | HDAC6 (0.59) | HDAC6ALDH1A1GAAMAPTMEN1 | |
| SCHEMBL3292874 | 0.82 | HDAC6 (0.59) | HDAC6ALDH1A1GAAMAPTMEN1 | |
| SCHEMBL379216 | 0.82 | GLO1 (0.59) | HDAC6ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL19631407 | 0.81 | HDAC6 (0.75) | HDAC6ALDH1A1GAAMAPTMEN1 | |
| SCHEMBL1008580 | 0.80 | GLO1 (0.61) | HDAC6MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL28232978 | 0.80 | SLC40A1 (0.61) | HDAC6MAPTRELAGLO1SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221677-B1 | P-AMINOPHENOLS, DERIVATIVES THEREOF AND USE FOR MANUFACTURE OF A MEDICAMENT | E.R. Squibb & Sons, Inc. (US) | 1992-09-09 | — | — | EP | claimed |