Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14430215 | 0.78 | GRM4 (0.43) | GRM4PRMT5HRH4LMNAHSP90AA1 | |
| SCHEMBL17261297 | 0.77 | HSP90AA1 (0.42) | PRMT5HRH4LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL23067956 | 0.74 | GRM4 (0.41) | GRM4PRMT5HRH4LMNAHSP90AA1 | |
| SCHEMBL17112234 | 0.73 | SMN1; SMN2 (0.42) | LMNAMAOBMAPTNPC1KDM4E | |
| SCHEMBL27359785 | 0.73 | GRM4 (0.40) | GRM4PRMT5HRH4LMNAHSP90AA1 | |
| SCHEMBL2914480 | 0.71 | MAPT (0.46) | HRH4LMNAMAPTKDM4EHTT | |
| SCHEMBL31052526 | 0.71 | HSP90AA1 (0.43) | PRMT5HRH4LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL17045432 | 0.71 | HSP90AA1 (0.43) | PRMT5HRH4LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL9123512 | 0.70 | GRM4 (0.62) | GRM4LMNAMAPTNPC1L3MBTL1 | |
| SCHEMBL9058058 | 0.67 | KDM4E (0.50) | PRMT5LMNAHSP90AA1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457200-A | Oxidative coupling reactions for determination of hydrogen peroxide | BOEHRINGER MANNHEIM (DE) | 1995-10-10 | — | — | US | claimed |