SCHEMBL9123782

SCHEMBL9123782

Cc1cc(C)c(C(Cl)C(Cl)(Cl)Cl)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9121770 0.74 SLC6A2 (0.35) RAPGEF4
SCHEMBL7705523 0.74 RAPGEF4 (0.39) RAPGEF4
SCHEMBL2848311 0.73 RAPGEF4 (0.43) RAPGEF4
SCHEMBL29613032 0.72 RAPGEF4 (0.38) RAPGEF4
SCHEMBL18567679 0.72 RAPGEF4 (0.43) RAPGEF4
SCHEMBL21259500 0.70 SLC6A2 (0.38) RAPGEF4
SCHEMBL22298450 0.70 SLC6A2 (0.38) RAPGEF4
SCHEMBL27927634 0.66 RAPGEF4 (0.41) RAPGEF4
SCHEMBL5163137 0.66 RAPGEF4 (0.41) RAPGEF4
SCHEMBL8468825 0.65 TP53 (0.35) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5457239-A Process for formylation of aromatic compounds UNION CAMP CORPORATION (US) 1995-10-10 US disclosed