Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 10/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29613032 | 0.97 | RAPGEF4 (0.38) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL893285 | 0.85 | ALDH1A1 (0.35) | ALDH1A1TSHRTP53TDP1CA1 | |
| SCHEMBL2848311 | 0.81 | RAPGEF4 (0.43) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL18567679 | 0.80 | RAPGEF4 (0.43) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL21259500 | 0.78 | SLC6A2 (0.38) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL22298450 | 0.78 | SLC6A2 (0.38) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL15318954 | 0.78 | KDM4E (0.31) | KDM4E | |
| SCHEMBL15318953 | 0.77 | — | — | |
| SCHEMBL9123782 | 0.74 | RAPGEF4 (0.33) | RAPGEF4 | |
| SCHEMBL5163137 | 0.73 | RAPGEF4 (0.41) | RAPGEF4ALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394895-B | Preparation method of 2,4, 6-trimethylphenylacetic acid | 西安凯立新材料股份有限公司 | 2023-09-15 | — | — | CN | claimed |
| CN-114394895-A | Preparation method of 2,4, 6-trimethylphenylacetic acid | 西安凯立新材料股份有限公司 | 2022-04-26 | — | — | CN | claimed |
| CN-119143726-A | Heterocyclic thiourea-containing ligand and preparation method and application thereof | 浙江药科职业大学 | 2024-12-17 | — | — | CN | disclosed |
| CN-114394895-B | Preparation method of 2,4, 6-trimethylphenylacetic acid | 西安凯立新材料股份有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-114394895-A | Preparation method of 2,4, 6-trimethylphenylacetic acid | 西安凯立新材料股份有限公司 | 2022-04-26 | — | — | CN | disclosed |
| US-6355826-B1 | HALOMETHYLATION AN AROMATIC ALDEHYDE COMPOUND AND SALT FORMATION | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-03-12 | — | — | US | disclosed |
| WO-2001016260-A1 | OLIGOMERIC POLYKETONES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2001-03-08 | — | — | WO | disclosed |
| EP-0903338-A2 | Synthesis of stable nitrile oxide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-03-24 | — | — | EP | disclosed |
| US-4101510-A | SUBSTITUTED VINYL AROMATIC MONOMER, LEWIS ACID | STANDARD OIL COMPANY A CORPORATION OF INDIANA (US) | 1978-07-18 | — | — | US | disclosed |