Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124996 | 0.82 | ALDH1A1 (0.38) | ALDH1A1TDP1 | |
| SCHEMBL9122183 | 0.81 | SMN1; SMN2 (0.36) | MAPTALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9125993 | 0.79 | CRHR1 (0.36) | TDP1 | |
| SCHEMBL1123483 | 0.79 | MAPT (0.42) | MAPTALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9126075 | 0.77 | MAPT (0.45) | MAPTALDH1A1TDP1 | |
| SCHEMBL9125112 | 0.75 | CRHR1 (0.34) | MAPTALDH1A1 | |
| SCHEMBL10998149 | 0.74 | MEN1 (0.34) | MAPTALDH1A1TDP1 | |
| SCHEMBL9121399 | 0.71 | KMT2A (0.48) | MAPTALDH1A1 | |
| SCHEMBL9124621 | 0.71 | MAPT (0.44) | MAPTALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9122466 | 0.69 | ALDH1A1 (0.37) | MAPTALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397781-A | Pyrimidine derivatives | MOCHIDA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0561175-A1 | Pyrimidine derivatives and pharmaceutical compostions containing them | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-22 | — | — | EP | disclosed |