Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.54 |
| ▸ | ESRRG | P62508 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28525779 | 0.95 | NPC1 (0.62) | MGLLNPC1RAB9AADAMTS4EPHX1 | |
| SCHEMBL10133046 | 0.92 | MGLL (0.65) | MGLLNPC1RAB9AADAMTS4EPHX1 | |
| SCHEMBL9126519 | 0.90 | NPC1 (0.60) | MGLLNPC1RAB9AADAMTS4EPHX1 | |
| SCHEMBL17552096 | 0.89 | NPC1 (0.69) | MGLLNPC1RAB9AADAMTS4EPHX1 | |
| SCHEMBL5108159 | 0.85 | NPC1 (0.69) | MGLLNPC1RAB9AEPHX1TAAR1 | |
| SCHEMBL27744398 | 0.85 | EPHX1 (0.70) | MGLLNPC1RAB9AADAMTS4EPHX1 | |
| SCHEMBL9126523 | 0.83 | MGLL (0.48) | MGLLNPC1RAB9AADAMTS4EPHX1 | |
| SCHEMBL30776776 | 0.83 | NPC1 (0.67) | MGLLNPC1RAB9AADAMTS4EPHX1 | |
| SCHEMBL9263805 | 0.83 | NPC1 (0.67) | MGLLNPC1RAB9AEPHX1TAAR1 | |
| SCHEMBL3274691 | 0.82 | FAAH (0.64) | MGLLNPC1RAB9AADAMTS4EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009009041-A2 | COMPOSITIONS AND METHODS FOR MODULATING A KINASE CASCADE | KINEX PHARMACEUTICALS, LLC (US) | 2009-01-15 | — | — | WO | disclosed |
| EP-0524419-B1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS (JP) | 1995-09-06 | — | — | EP | disclosed |
| US-5391806-A | A storage stable chromogens as color-developing agent or stabilizers | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5270281-A | Chromogenic compound | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0524419-A1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-27 | — | — | EP | disclosed |