Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9123708 | 0.88 | ALDH1A1 (0.37) | ALDH1A1MAPT | |
| SCHEMBL9124238 | 0.86 | MAPT (0.36) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL9124018 | 0.85 | TDP1 (0.38) | ALDH1A1MAPTTDP1GAASMN1; SMN2 | |
| SCHEMBL9125254 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPTTDP1GAARAB9A | |
| SCHEMBL9123369 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MAPTTDP1GAARAB9A | |
| SCHEMBL9121830 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MAPTTDP1GAASMN1; SMN2 | |
| SCHEMBL11220123 | 0.78 | TDP1 (0.37) | ALDH1A1MAPTTDP1GAASMN1; SMN2 | |
| SCHEMBL9122183 | 0.78 | SMN1; SMN2 (0.36) | ALDH1A1MAPTTDP1GAASMN1; SMN2 | |
| SCHEMBL9124844 | 0.78 | MAPT (0.37) | ALDH1A1MAPTTDP1GAASMN1; SMN2 | |
| SCHEMBL10749387 | 0.76 | CA1 (0.43) | ALDH1A1MAPTSMN1; SMN2HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397781-A | Pyrimidine derivatives | MOCHIDA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0561175-A1 | Pyrimidine derivatives and pharmaceutical compostions containing them | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-22 | — | — | EP | disclosed |