Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | PPIA | P62937 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124018 | 0.88 | TDP1 (0.38) | TDP1GAAMAP2K7SMN1; SMN2ALDH1A1 | |
| SCHEMBL9122183 | 0.81 | SMN1; SMN2 (0.36) | TDP1GAASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9124844 | 0.81 | MAPT (0.37) | TDP1GAASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL596867 | 0.78 | TDP1 (0.38) | TDP1ALDH1A1MAPTL3MBTL1ALPL | |
| SCHEMBL9124609 | 0.78 | ALDH1A1 (0.39) | TDP1GAASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11499585 | 0.76 | TDP1 (0.50) | TDP1GAAALDH1A1MAPTRAB9A | |
| SCHEMBL28759722 | 0.74 | TDP1 (0.46) | TDP1GAASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7078865 | 0.73 | MAPT (0.37) | TDP1SMN1; SMN2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9124973 | 0.73 | CRHR1 (0.48) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL6295020 | 0.71 | CRHR1 (0.42) | TDP1MAPTMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57035591-A | — | — | None | — | — | JP | disclosed |
| JP-S5735591-A | NOVEL PYRIMIDINE DERIVATIVE | MOCHIDA PHARMACEUT CO LTD | 1982-02-26 | — | — | JP | disclosed |