SCHEMBL912495

SCHEMBL912495

OC(c1ccccc1)(c1ccccc1)c1ccccn1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.78
SMN1; SMN2 Q16637 1/20 0.78
AHR P35869 2/20 0.56
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
CFTR P13569 1/20 0.47
GOPC Q9HD26 1/20 0.47
CHRM3 P20309 1/20 0.44
TDP1 Q9NUW8 2/20 0.44
CHRM2 P08172 1/20 0.44
CYP19A1 P11511 2/20 0.43
HDAC6 Q9UBN7 2/20 0.43
BLM P54132 2/20 0.40
LMNA P02545 1/20 0.40
NAPRT Q6XQN6 1/20 0.40
P4HTM Q9NXG6 1/20 0.40
CYP2D6 P10635 1/20 0.40
SLC22A2 O15244 1/20 0.40
SLC22A1 O15245 1/20 0.40
PGR P06401 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29410666 1.00 L3MBTL1 (0.78) L3MBTL1SMN1; SMN2AHRKMT2AMEN1
SCHEMBL2490118 0.98 SMN1; SMN2 (0.75) L3MBTL1SMN1; SMN2AHRKMT2AMEN1
SCHEMBL4464386 0.89 SMN1; SMN2 (0.62) L3MBTL1SMN1; SMN2AHRCYP19A1CYP3A4
SCHEMBL2454601 0.88 L3MBTL1 (1.00) L3MBTL1SMN1; SMN2AHRKMT2AMEN1
SCHEMBL6579906 0.88 SMN1; SMN2 (0.67) L3MBTL1SMN1; SMN2AHRKMT2AMEN1
SCHEMBL11557390 0.86 AHR (0.60) L3MBTL1SMN1; SMN2AHRKMT2AMEN1
SCHEMBL15854868 0.84 AHR (0.81) L3MBTL1SMN1; SMN2AHRKMT2AMEN1
SCHEMBL22319803 0.84 SMN1; SMN2 (0.56) L3MBTL1SMN1; SMN2AHRKMT2AMEN1
SCHEMBL3045407 0.84 SMN1; SMN2 (0.67) L3MBTL1SMN1; SMN2AHRCYP19A1CYP3A4
SCHEMBL13714141 0.82 SMN1; SMN2 (0.53) L3MBTL1SMN1; SMN2AHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109651238-A A kind of new method preparing picosulfate sodium 杭州新博思生物医药有限公司 2019-04-19 CN claimed
US-9422375-B2 Non-cyclopentadienyl-based chromium catalysts for olefin polymerization DOW GLOBAL TECHNOLOGIES LLC 2016-08-23 US claimed
US-9296836-B2 Non-cyclopentadienyl-based chromium catalysts for olefin polymerization DOW GLOBAL TECHNOLOGIES LLC 2016-03-29 US claimed
US-20160053031-A1 NON-CYCLOPENTADIENYL-BASED CHROMIUM CATALYSTS FOR OLEFIN POLYMERIZATION DOW GLOBAL TECHNOLOGIES LLC 2016-02-25 US claimed
US-20150148502-A1 NON-CYCLOPENTADIENYL-BASED CHROMIUM CATALYSTS FOR OLEFIN POLYMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2015-05-28 US claimed
WO-2012155022-A1 NON-CYCLOPENTADIENYL-BASED CHROMIUM CATALYSTS FOR OLEFIN POLYMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2012-11-15 WO claimed
US-5541331-A Processes for producing α-pyridyl carbinols REILLY INDUSTRIES, INC. (US) 1996-07-30 US claimed
JP-60069111-A None JP disclosed
EP-4508101-B1 PROCESS FOR MANUFACTURING OF POLYISOBUTENE SUCCINIC ANHYDRIDES BASF SE (DE) 2026-03-25 EP disclosed
EP-4667447-A1 PROCESS FOR THE PREPARATION OF POLYISOBUTENE FROM BIO-BASED OLEFINS FROM PRIMARY ALCOHOL BASF SE (DE) 2025-12-24 EP disclosed
US-20250250403-A1 PROCESS FOR MANUFACTURING OF POLYISOBUTENE SUCCINIC ANHYDRIDES BASF SE (DE) 2025-08-07 US disclosed
WO-2025082909-A1 PROCESS FOR IMPROVING THE STABILITY OF POLYISOBUTENES BASF SE (DE) 2025-04-24 WO disclosed
EP-4476273-A1 MEDIUM MOLECULAR POLYISOBUTENE WITH A HIGH CONTENT OF CERTAIN DOUBLE BOND ISOMERS BASF SE (DE) 2024-12-18 EP disclosed
WO-1997034589-A1 TRIARYL METHANE COMPOUNDS FOR SICKLE CELL DISEASE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1997-09-25 WO disclosed
US-5541331-A Processes for producing α-pyridyl carbinols REILLY INDUSTRIES, INC. (US) 1996-07-30 US disclosed
EP-0330875-B1 Process for the preparation of tertiary carbinols containing an aminic substituent LEPETIT SPA (IT) 1995-08-16 EP disclosed
EP-0641322-A1 PROCESSES FOR PRODUCING $g(a)-PYRIDYL CARBINOLS REILLY INDUSTRIES, INC. (US) 1995-03-08 EP disclosed
WO-1992019596-A2 PROCESSES FOR PRODUCING α-PYRIDYL CARBINOLS REILLY INDUSTRIES, INC. (US) 1992-11-12 WO disclosed
EP-0330875-A2 Process for the preparation of tertiary carbinols containing an aminic substituent GRUPPO LEPETIT S.p.A. (IT) 1989-09-06 EP disclosed
JP-S6069111-A 2-PYRIDYL GROUP-CONTAINING ORGANIC POLYMER DAICEL CHEM IND LTD 1985-04-19 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150148502-A1 NON-CYCLOPENTADIENYL-BASED CHROMIUM CATALYSTS FOR OLEFIN POLYMERIZATION CRKL, HCK, CCRL2 L3MBTL1 1324/4885SMN1; SMN2 2989/4885AHR 243/4885
US-20160053031-A1 NON-CYCLOPENTADIENYL-BASED CHROMIUM CATALYSTS FOR OLEFIN POLYMERIZATION CRKL, HCK, CCRL2 L3MBTL1 1324/4885SMN1; SMN2 2989/4885AHR 243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.