Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3688679 | 0.80 | KDM4E (0.41) | KDM4EALDH1A1L3MBTL1HCAR2LMNA | |
| SCHEMBL9734881 | 0.79 | NOTUM (0.45) | KDM4EALDH1A1GAASMN1; SMN2LMNA | |
| SCHEMBL9875374 | 0.75 | HTT (0.33) | HTTKDM4EALDH1A1GAANPSR1 | |
| SCHEMBL2591258 | 0.74 | GAA (0.49) | HTTKDM4ETSHRALDH1A1GAA | |
| SCHEMBL2383891 | 0.73 | HTT (0.44) | HTTKDM4ETSHRGAASMN1; SMN2 | |
| SCHEMBL9734970 | 0.72 | HTT (0.41) | HTTKDM4ETSHRGAASMN1; SMN2 | |
| SCHEMBL7100600 | 0.72 | HTT (0.41) | HTTKDM4ETSHRALDH1A1GAA | |
| SCHEMBL31531675 | 0.71 | HTT (0.40) | HTTKDM4ETSHRGAASMN1; SMN2 | |
| SCHEMBL7101660 | 0.71 | PBRM1 (0.35) | HTTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13208612 | 0.70 | HTT (0.42) | HTTKDM4ETSHRGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475113-A | Treatment of skin disorders, skin cancer | ALLERGAN, INC. (US) | 1995-12-12 | — | — | US | disclosed |