Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.32 |
| ▸ | CDK1 | P06493 | 2/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876151 | 0.76 | HTT (0.36) | HTTTP53ALDH1A1MCOLN3KDM4E | |
| SCHEMBL9125151 | 0.75 | HTT (0.41) | HTTTP53ALDH1A1KMT2AKDM4E | |
| SCHEMBL9876039 | 0.72 | CCNB2 (0.32) | HTTCCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL9876018 | 0.70 | ALPL (0.41) | TP53ALDH1A1MCOLN3KDM4ELMNA | |
| SCHEMBL9734881 | 0.69 | NOTUM (0.45) | TP53ALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL14248095 | 0.69 | PLAU (0.41) | — | |
| SCHEMBL7100834 | 0.68 | ALDH1A1 (0.45) | HTTTP53ALDH1A1KMT2AKDM4E | |
| SCHEMBL7100870 | 0.66 | HTT (0.42) | HTTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL2591258 | 0.65 | GAA (0.49) | HTTTP53ALDH1A1KMT2AKDM4E | |
| SCHEMBL7101660 | 0.64 | PBRM1 (0.35) | HTTALDH1A1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045557-A | Imidazable fungicides and use thereof | SCHERING AGROCHEMICALS LTD. (GB) | 1991-09-03 | — | — | US | disclosed |
| EP-0284277-A1 | Cyanoimidazole fungicides | AgrEvo UK Limited (GB) | 1988-09-28 | — | — | EP | disclosed |