SCHEMBL9734970

SCHEMBL9734970

CN(C)S(=O)(=O)n1cnc(CO)c1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.41
SORD Q00796 1/20 0.36
FGFR1 P11362 1/20 0.35
FGFR2 P21802 1/20 0.35
FGFR4 P22455 1/20 0.35
FGFR3 P22607 1/20 0.35
KDR P35968 1/20 0.35
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16523107 0.83 HTT (0.41) HTTFGFR1FGFR2FGFR4FGFR3
Hydrochloric Acid SCHEMBL31531698 0.81 HTT (0.40) HTTFGFR1FGFR2FGFR4FGFR3
SCHEMBL502375 0.80 HTT (0.39) HTTFGFR1FGFR2FGFR4FGFR3
SCHEMBL20808356 0.80 HTT (0.39) HTTFGFR1FGFR2FGFR4FGFR3
SCHEMBL13384283 0.80 HTT (0.39) HTTFGFR1FGFR2FGFR4FGFR3
SCHEMBL7260183 0.80 HTT (0.39) HTTFGFR1FGFR2FGFR4FGFR3
SCHEMBL7256301 0.79 FGFR1 (0.38) HTTFGFR1FGFR2FGFR4FGFR3
SCHEMBL30871722 0.78 ALDH1A1 (0.40) HTTFGFR1FGFR2FGFR4FGFR3
SCHEMBL7261739 0.78 HTT (0.37) HTTFGFR1FGFR2FGFR4FGFR3
SCHEMBL502126 0.76 HTT (0.36) HTTFGFR1FGFR2FGFR4FGFR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132126-A1 IMIDAZOLE DERIVATIVES SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 2026-05-14 US disclosed
EP-4603489-A1 IMIDAZOLE DERIVATIVE SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 2025-08-20 EP disclosed
CN-119998277-A Imidazole derivatives 株式会社三和化学研究所 2025-05-13 CN disclosed
WO-2024080361-A1 IMIDAZOLE DERIVATIVE 株式会社 三和化学研究所 2024-04-18 WO disclosed
EP-2776436-B1 NEW COMPOUNDS ASTEX THERAPEUTICS LTD (GB) 2019-03-13 EP disclosed
US-9757364-B2 Naphthyridine derivative compounds ASTEX THERAPEUTICS LTD (GB) 2017-09-12 US disclosed
US-9757364-B2 Naphthyridine derivative compounds ASTEX THERAPEUTICS LTD (GB) 2017-09-12 US disclosed
US-20170105978-A1 NEW COMPOUNDS ASTEX THERAPEUTICS LIMITED (GB) 2017-04-20 US disclosed
US-20170105978-A1 NEW COMPOUNDS ASTEX THERAPEUTICS LIMITED (GB) 2017-04-20 US disclosed
US-9527844-B2 Naphthyridine derivative compounds ASTEX THERAPEUTICS LIMITED (GB) 2016-12-27 US disclosed
US-9527844-B2 Naphthyridine derivative compounds ASTEX THERAPEUTICS LIMITED (GB) 2016-12-27 US disclosed
US-20160108034-A1 NAPHTHYRIDINE DERIVATIVE COMPOUNDS ASTEX THERAPEUTICS LIMITED (GB) 2016-04-21 US disclosed
US-9309241-B2 Naphthyridine derivative compounds ASTEX THERAPEUTICS LTD (GB) 2016-04-12 US disclosed
US-9309241-B2 Naphthyridine derivative compounds ASTEX THERAPEUTICS LTD (GB) 2016-04-12 US disclosed
US-20150057293-A1 NEW COMPOUNDS ASTEX THERAPEUTICS LIMITED (GB) 2015-02-26 US disclosed
US-20150057293-A1 NEW COMPOUNDS ASTEX THERAPEUTICS LIMITED (GB) 2015-02-26 US disclosed
US-5096915-A For phytopathogens SCHERING AGROCHEMICALS (GB) 1992-03-17 US disclosed
EP-0390506-A1 Azole fungicides AgrEvo UK Limited (GB) 1990-10-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150057293-A1 NEW COMPOUNDS NQO1, NTPCR, NDC1 HTT 283/4885SORD 977/4885FGFR1 2337/4885
US-20260132126-A1 IMIDAZOLE DERIVATIVES ADRA1A, ADRA1D, ADRB1 HTT 4347/4885SORD 2165/4885FGFR1 500/4885
US-20170105978-A1 NEW COMPOUNDS NQO1, NTPCR, NDC1 HTT 283/4885SORD 977/4885FGFR1 2337/4885
US-20160108034-A1 NAPHTHYRIDINE DERIVATIVE COMPOUNDS NQO1, NDC1, NTPCR HTT 316/4885SORD 517/4885FGFR1 1630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.