Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438315 | 1.00 | KCNJ1 (0.39) | KCNJ1KCNH2HRH2HRH1SIGMAR1 | |
| SCHEMBL8543784 | 0.88 | KCNJ1 (0.39) | KCNJ1KCNH2HRH2HRH1SIGMAR1 | |
| SCHEMBL8438015 | 0.88 | KCNJ1 (0.39) | KCNJ1KCNH2HRH2HRH1SIGMAR1 | |
| SCHEMBL8536750 | 0.86 | KCNJ1 (0.42) | KCNJ1KCNH2HRH2HRH1SIGMAR1 | |
| SCHEMBL8438589 | 0.86 | KCNJ1 (0.42) | KCNJ1KCNH2HRH2HRH1SIGMAR1 | |
| SCHEMBL8440034 | 0.85 | KCNJ1 (0.41) | KCNJ1KCNH2HRH2HRH1SIGMAR1 | |
| SCHEMBL8439555 | 0.83 | KCNJ1 (0.41) | KCNJ1KCNH2HRH2HRH1SIGMAR1 | |
| SCHEMBL8437949 | 0.83 | TDP1 (0.42) | CCR5ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8437950 | 0.83 | TDP1 (0.42) | CCR5ALDH1A1MAPTSMN1; SMN2 | |
| Trifluoromethanesulfonic Acid SCHEMBL8537325 | 0.80 | CCR5 (0.37) | KCNJ1KCNH2HRH2HRH1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420119-A | Bactericides | SANKYO COMPANY, LIMITED (JP) | 1995-05-30 | — | — | US | disclosed |
| US-5310735-A | Carbapenem derivatives having antibiotic activity, their preparation and their use | SANKYO COMPANY, LIMITED (JP) | 1994-05-10 | — | — | US | disclosed |