Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28170944 | 0.89 | RAB9A (0.58) | POLBRAB9ANPC1HPGDCRHBP | |
| SCHEMBL9125831 | 0.82 | MEN1 (0.52) | ESR1POLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11145638 | 0.80 | ESR1 (0.61) | ESR1RAB9ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL10165811 | 0.79 | SMN1; SMN2 (0.62) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL7565510 | 0.77 | RAB9A (0.71) | POLBRAB9ANPC1HPGDCRHBP | |
| SCHEMBL11396210 | 0.77 | RAB9A (0.55) | POLBRAB9ANPC1HPGDCRHBP | |
| SCHEMBL10447891 | 0.77 | SMN1; SMN2 (0.63) | RAB9ANPC1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL11145632 | 0.76 | HSP90AA1 (0.57) | ESR1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9126915 | 0.75 | ESR1 (0.50) | ESR1POLBHSD17B10CYP2D6SMN1; SMN2 | |
| SCHEMBL29696084 | 0.75 | ESR1 (0.95) | ESR1HPGDHSD17B10ALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524419-B1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS (JP) | 1995-09-06 | — | — | EP | disclosed |
| US-5391806-A | A storage stable chromogens as color-developing agent or stabilizers | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5270281-A | Chromogenic compound | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0524419-A1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-27 | — | — | EP | disclosed |