Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 1/20 | 0.48 |
| ▸ | TLR4 | O00206 | 13/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.43 |
| ▸ | LY96 | Q9Y6Y9 | 6/20 | 0.42 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GALK1 | P51570 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129443 | 0.95 | TLR4 (0.52) | LGALS8TLR4SELPLY96 | |
| SCHEMBL9125890 | 0.95 | TLR4 (0.52) | LGALS8TLR4SELPLY96 | |
| SCHEMBL9123429 | 0.92 | LGALS8 (0.48) | LGALS8TLR4SELPLY96 | |
| SCHEMBL9127387 | 0.90 | LGALS8 (0.46) | LGALS8TLR4SELPLY96SYNJ2 | |
| SCHEMBL9124937 | 0.90 | LGALS8 (0.46) | LGALS8TLR4SELPLY96SYNJ2 | |
| SCHEMBL9127101 | 0.89 | TLR4 (0.39) | LGALS8TLR4SELP | |
| SCHEMBL9124847 | 0.88 | TLR4 (0.46) | LGALS8TLR4SELPLY96 | |
| SCHEMBL9124840 | 0.88 | TLR4 (0.46) | LGALS8TLR4SELPLY96 | |
| SCHEMBL9126778 | 0.88 | TLR4 (0.46) | LGALS8TLR4SELPLY96 | |
| SCHEMBL9124536 | 0.84 | TLR4 (0.42) | LGALS8TLR4SELPLY96 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432267-A | Inhibits tumor necrosis factor derivation by endotoxin | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0563908-A1 | Amino sugar derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |