Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 8/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 5/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 5/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | SELP | P16109 | 3/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9127437 | 0.93 | TLR4 (0.39) | TLR4LGALS8SSTR3SSTR5SELP | |
| SCHEMBL9126967 | 0.89 | LGALS8 (0.48) | TLR4LGALS8SELP | |
| SCHEMBL9123773 | 0.88 | TLR4 (0.42) | TLR4LGALS8SSTR3SSTR5MCHR1 | |
| SCHEMBL9124536 | 0.86 | TLR4 (0.42) | TLR4LGALS8SSTR3SSTR5SELP | |
| SCHEMBL9127454 | 0.86 | TLR4 (0.42) | TLR4LGALS8SSTR3SSTR5SELP | |
| SCHEMBL9126379 | 0.85 | TLR4 (0.42) | TLR4LGALS8SSTR3SSTR5SELP | |
| SCHEMBL9125890 | 0.85 | TLR4 (0.52) | TLR4LGALS8SELP | |
| SCHEMBL9129443 | 0.85 | TLR4 (0.52) | TLR4LGALS8SELP | |
| SCHEMBL9126017 | 0.84 | TLR4 (0.41) | TLR4LGALS8SSTR3SSTR5SELP | |
| SCHEMBL9127067 | 0.84 | TLR4 (0.41) | TLR4LGALS8SSTR3SSTR5SELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432267-A | Inhibits tumor necrosis factor derivation by endotoxin | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0563908-A1 | Amino sugar derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |