Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HK1 | P19367 | 1/20 | 0.39 |
| ▸ | HK2 | P52789 | 1/20 | 0.39 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9127088 | 1.00 | CA1 (0.43) | CA1CA2CA9HDAC3HDAC4 | |
| SCHEMBL9125990 | 0.90 | HDAC6 (0.41) | CA1CA2CA9HDAC3HDAC4 | |
| SCHEMBL9126001 | 0.90 | HDAC6 (0.41) | CA1CA2CA9HDAC3HDAC4 | |
| SCHEMBL9127547 | 0.82 | MAPK1 (0.52) | — | |
| SCHEMBL9129410 | 0.81 | LMNA (0.51) | CA1CA2CA9HDAC3HDAC4 | |
| SCHEMBL9129405 | 0.81 | LMNA (0.51) | CA1CA2CA9HDAC3HDAC4 | |
| SCHEMBL9124847 | 0.81 | TLR4 (0.46) | — | |
| SCHEMBL9124840 | 0.81 | TLR4 (0.46) | — | |
| SCHEMBL9126778 | 0.81 | TLR4 (0.46) | — | |
| SCHEMBL9127387 | 0.79 | LGALS8 (0.46) | SYNJ2KDM4EABL1ALPLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432267-A | Inhibits tumor necrosis factor derivation by endotoxin | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0563908-A1 | Amino sugar derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |