Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17549813 | 0.82 | RAB9A (0.60) | NPC1RAB9AFAAHLMNASMN1; SMN2 | |
| SCHEMBL9123632 | 0.80 | MAPT (0.58) | NPC1RAB9ALMNASMN1; SMN2MEN1 | |
| SCHEMBL9127366 | 0.80 | MAPT (0.58) | NPC1RAB9ALMNASMN1; SMN2MEN1 | |
| SCHEMBL13029379 | 0.79 | ESR1 (0.53) | LMNAMEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL25851017 | 0.77 | KMT2A (0.57) | NPC1RAB9ALMNASMN1; SMN2MEN1 | |
| SCHEMBL14524519 | 0.77 | RAB9A (0.45) | NPC1RAB9AFAAHNR1H4SMN1; SMN2 | |
| SCHEMBL9129143 | 0.76 | KDM4E (0.48) | NPC1RAB9ALMNASMN1; SMN2MEN1 | |
| SCHEMBL9124950 | 0.76 | ALDH1A1 (0.47) | LMNASMN1; SMN2HPGDHSD17B10KDM4E | |
| SCHEMBL28525779 | 0.76 | NPC1 (0.62) | NPC1RAB9AHPGDHSD17B10ALDH1A1 | |
| SCHEMBL25612493 | 0.76 | ESR1 (0.53) | LMNAMEN1KMT2AL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524419-B1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS (JP) | 1995-09-06 | — | — | EP | disclosed |
| US-5391806-A | A storage stable chromogens as color-developing agent or stabilizers | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5270281-A | Chromogenic compound | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0524419-A1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-27 | — | — | EP | disclosed |