Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126171 | 0.96 | ALDH1A1 (0.38) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| SCHEMBL8439023 | 0.95 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| SCHEMBL8436267 | 0.93 | ALDH1A1 (0.40) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| SCHEMBL8436746 | 0.91 | GPR119 (0.41) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| SCHEMBL9126554 | 0.88 | GAA (0.40) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| SCHEMBL8436337 | 0.87 | ALDH1A1 (0.36) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| SCHEMBL9127639 | 0.86 | KCNJ1 (0.41) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| SCHEMBL9127478 | 0.86 | KCNJ1 (0.40) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| SCHEMBL8575147 | 0.85 | GAA (0.41) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL8579624 | 0.85 | GAA (0.40) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420119-A | Bactericides | SANKYO COMPANY, LIMITED (JP) | 1995-05-30 | — | — | US | disclosed |
| US-5310735-A | Carbapenem derivatives having antibiotic activity, their preparation and their use | SANKYO COMPANY, LIMITED (JP) | 1994-05-10 | — | — | US | disclosed |