Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20837322 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HPGDGAAEPHX2TSHR | |
| SCHEMBL2681321 | 0.80 | TSHR (0.57) | ALDH1A1HPGDGAAEPHX2TSHR | |
| SCHEMBL1778423 | 0.80 | TSHR (0.57) | ALDH1A1HPGDGAAEPHX2TSHR | |
| SCHEMBL7478058 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HPGDGAAEPHX2TSHR | |
| SCHEMBL10202112 | 0.80 | TSHR (0.57) | ALDH1A1HPGDGAAEPHX2TSHR | |
| SCHEMBL14930583 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HPGDGAAEPHX2TSHR | |
| SCHEMBL10202307 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HPGDGAAEPHX2TSHR | |
| SCHEMBL14291922 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HPGDGAAEPHX2TSHR | |
| Hydrochloric Acid SCHEMBL2057759 | 0.78 | TSHR (0.55) | ALDH1A1HPGDGAAEPHX2TSHR | |
| SCHEMBL22541537 | 0.77 | DPP4 (0.38) | HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453504-A | Useful for synthesis of beta lactam antibiotics | ELI LILLY AND COMPANY (US) | 1995-09-26 | — | — | US | disclosed |
| US-5391728-A | Bicyclic B-lactams intermediates having a new amino protecting group | ELI LILLY AND COMPANY (US) | 1995-02-21 | — | — | US | disclosed |
| US-5283329-A | Amino protecting group | ELI LILLY AND COMPANY (US) | 1994-02-01 | — | — | US | disclosed |
| US-5239069-A | Amino protecting group | ELI LILLY AND COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| US-5169945-A | Amino protecting group | ELI LILLY AND COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0457512-A2 | New amino protecting group | ELI LILLY AND COMPANY (US) | 1991-11-21 | — | — | EP | disclosed |