Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14930583 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HPGDGAATSHRPOLB | |
| SCHEMBL10202307 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HPGDGAATSHRPOLB | |
| SCHEMBL20203666 | 0.94 | ALDH1A1 (0.57) | ALDH1A1HPGDGAATSHRPOLB | |
| SCHEMBL7107767 | 0.94 | ALDH1A1 (0.57) | ALDH1A1HPGDGAATSHRPOLB | |
| SCHEMBL14291922 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HPGDGAATSHRHSD17B10 | |
| SCHEMBL20837322 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HPGDGAATSHRPOLB | |
| SCHEMBL9127779 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HPGDGAATSHRPOLB | |
| SCHEMBL26258441 | 0.79 | KMT2A (0.48) | ALDH1A1HPGDGAATSHRHSD17B10 | |
| SCHEMBL13652928 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HPGDGAATSHRPOLB | |
| SCHEMBL4021879 | 0.78 | HPGD (0.52) | ALDH1A1HPGDGAATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1250332-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | Abbott Laboratories (US) | 2002-10-23 | — | — | EP | claimed |
| WO-2001044223-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | ABBOTT LABORATORIES (US) | 2001-06-21 | — | — | WO | claimed |
| US-11324738-B2 | Muscarinic agonists | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-05-10 | — | — | US | disclosed |
| EP-3331528-B1 | MUSCARINIC AGONISTS | HEPTARES THERAPEUTICS LTD (GB) | 2021-09-29 | — | — | EP | disclosed |
| US-10779540-B2 | Benzamide compounds and their use as herbicides | BASF SE (DE) | 2020-09-22 | — | — | US | disclosed |
| EP-3390372-B1 | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2020-06-03 | — | — | EP | disclosed |
| US-20200129496-A1 | MUSCARINIC AGONISTS | NXERA PHARMA UK LIMITED (GB) | 2020-04-30 | — | — | US | disclosed |
| US-10548884-B2 | Muscarinic agonists | HEPTARES THERAPEUTICS LIMITED (GB) | 2020-02-04 | — | — | US | disclosed |
| WO-2019243850-A1 | OXADIAZOLES AS AGONISTS OF THE MUSCARINIC M1 AND/OR M4 RECEPTOR | HEPTARES THERAPEUTICS LIMITED (GB) | 2019-12-26 | — | — | WO | disclosed |
| EP-2773634-B1 | ROD-LIKE HEPATITIS C VIRUS INHIBITORS CONTAINING THE FRAGEMENT {2-[4-(BIPHENYL-4-YL)-1H-IMIDAZO-2-YL]PYRROLIDINE-1-CARBONLYMETHYL}AMINE | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2018-06-06 | — | — | EP | disclosed |
| WO-2017102275-A1 | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2017-06-22 | — | — | WO | disclosed |
| WO-2017021728-A9 | MUSCARINIC AGONISTS | HEPTARES THERAPEUTICS LIMTED (GB) | 2017-04-27 | — | — | WO | disclosed |
| WO-2017021728-A1 | MUSCARINIC AGONISTS | HEPTARES THERAPEUTICS LIMTED (GB) | 2017-02-09 | — | — | WO | disclosed |
| EP-1250332-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | Abbott Laboratories (US) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001044223-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | ABBOTT LABORATORIES (US) | 2001-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10548884-B2 | Muscarinic agonists | CHRM1, CHRM2, CHRM4 | ALDH1A1 2074/4885HPGD 2685/4885GAA 3715/4885 |
| US-10779540-B2 | Benzamide compounds and their use as herbicides | DDT, DNPH1, BBOX1 | ALDH1A1 74/4885HPGD 907/4885GAA 421/4885 |
| US-20200129496-A1 | MUSCARINIC AGONISTS | CHRM1, CHRM2, CHRM4 | ALDH1A1 1921/4885HPGD 2600/4885GAA 3708/4885 |
| US-11324738-B2 | Muscarinic agonists | CHRM1, CHRM2, CHRM4 | ALDH1A1 1921/4885HPGD 2600/4885GAA 3708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.