Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL29567735 | 1.00 | ACHE (0.39) | ACHENFE2L2CES2CES1TAAR1 | |
| SCHEMBL123954 | 0.97 | ACHE (0.41) | ACHENFE2L2CES2CES1TAAR1 | |
| SCHEMBL1450796 | 0.94 | ACHE (0.39) | ACHENFE2L2CES2CES1TAAR1 | |
| SCHEMBL29830966 | 0.94 | ACHE (0.39) | ACHENFE2L2CES2CES1TAAR1 | |
| SCHEMBL1452107 | 0.94 | ACHE (0.39) | ACHENFE2L2CES2CES1TAAR1 | |
| Silver SCHEMBL1450856 | 0.94 | ACHE (0.39) | ACHENFE2L2CES2CES1TAAR1 | |
| Bromide SCHEMBL7211405 | 0.92 | ACHE (0.38) | ACHENFE2L2CES2CES1TAAR1 | |
| Bromide SCHEMBL7211403 | 0.92 | ACHE (0.38) | ACHENFE2L2CES2CES1TAAR1 | |
| Lithium Ion SCHEMBL1493096 | 0.82 | CES2 (0.40) | ACHENFE2L2CES2CES1TAAR1 | |
| SCHEMBL20841980 | 0.81 | ACHE (0.35) | ACHENFE2L2CES2CES1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638569-A1 | SUPPORTED MEMBRANES BY THERMAL AND UV INITIATED MASS POLYMERIZATION | Promerus, LLC (US) | 2025-10-29 | — | — | EP | claimed |
| EP-4584309-A1 | POLYCYCLIC-OLEFINIC POLYMERS CONTAINING ACRYLATE FUNCTIONALITY WITH ACRYLATE/MALEIMIDE CROSSLINKERS AS B-STAGEABLE COMPOSITIONS FOR LOW LOSS APPLICATIONS | Promerus, LLC (US) | 2025-07-16 | — | — | EP | claimed |
| US-12251668-B2 | Supported membranes by thermal and UV initiated mass polymerization | PROMERUS, LLC (US) | 2025-03-18 | — | — | US | claimed |
| EP-4504803-A1 | PALLADIUM CATALYSTS FOR FORMING VINYL ADDITION POLYMERS HAVING IMPROVED FILM FORMING PROPERTIES | Promerus, LLC (US) | 2025-02-12 | — | — | EP | claimed |
| US-20240216875-A1 | SUPPORTED MEMBRANES BY THERMAL AND UV INITITATED MASS POLYMERIZATION | PROMERUS, LLC (US) | 2024-07-04 | — | — | US | claimed |
| WO-2024137739-A1 | SUPPORTED MEMBRANES BY THERMAL AND UV INITIATED MASS POLYMERIZATION | PROMERUS, LLC (US) | 2024-06-27 | — | — | WO | claimed |
| US-20240141087-A1 | POLYCYCLIC-OLEFINIC POLYMERS CONTAINING ACRYLATE FUNCTIONALITY WITH ACRYLATE/MALEIMIDE CROSSLINKERS AS B-STAGEABLE COMPOSITIONS FOR LOW LOSS APPLICATIONS | PROMERUS, LLC (US) | 2024-05-02 | — | — | US | claimed |
| WO-2024054548-A1 | POLYCYCLIC-OLEFINIC POLYMERS CONTAINING ACRYLATE FUNCTIONALITY WITH ACRYLATE/MALEIMIDE CROSSLINKERS AS B-STAGEABLE COMPOSITIONS FOR LOW LOSS APPLICATIONS | PROMERUS, LLC (US) | 2024-03-14 | — | — | WO | claimed |
| US-11845880-B2 | Polycyclic-olefinic compositions for low-loss films having improved thermal properties | PROMERUS, LLC (US) | 2023-12-19 | — | — | US | claimed |
| WO-2023196366-A1 | PALLADIUM CATALYSTS FOR FORMING VINYL ADDITION POLYMERS HAVING IMPROVED FILM FORMING PROPERTIES | PROMERUS, LLC (US) | 2023-10-12 | — | — | WO | claimed |
| US-20170058145-A1 | POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS | PROMERUS, LLC (US) | 2017-03-02 | — | — | US | claimed |
| US-20160289353-A1 | CHAIN TRANSFER AGENT FOR ADDITION MASS POLYMERIZATION OF POLYCYCLOOLEFINIC MONOMERS | SUMITOMO BAKELITE CO., LTD. (JP) | 2016-10-06 | — | — | US | claimed |
| US-9415354-B2 | Organopalladium compounds as polymerization catalysts | PROMERUS, LLC (US) | 2016-08-16 | — | — | US | claimed |
| US-20160046657-A1 | ORGANOPALLADIUM COMPOUNDS AS POLYMERIZATION CATALYSTS | SUMITOMO BAKELITE CO., LTD. (JP) | 2016-02-18 | — | — | US | claimed |
| EP-1034196-B1 | CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS | PROMERUS LLC (US) | 2005-01-12 | — | — | EP | claimed |
| US-20030023013-A1 | Catalyst and methods for polymerizing cycloolefins | THE B.F.GOODRICH COMPANY | 2003-01-30 | — | — | US | claimed |
| US-6455650-B1 | CONTACTING POLYCYCLOOLEFIN MONOMER WITH A HIGH ACTIVITY GROUP 10 TRANSITION METAL CATALYST COMPLEX TO OBTAIN POLYMER PRODUCT | THE B.F. GOODRICH COMPANY | 2002-09-24 | — | — | US | claimed |
| US-20020052454-A1 | CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS | SUMITOMO BAKELITE CO., LTD. (JP) | 2002-05-02 | — | — | US | claimed |
| EP-1034196-A1 | CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS | THE B.F. GOODRICH COMPANY (US) | 2000-09-13 | — | — | EP | claimed |
| WO-2000020472-A1 | CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS | THE B.F. GOODRICH COMPANY (US) | 2000-04-13 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046657-A1 | ORGANOPALLADIUM COMPOUNDS AS POLYMERIZATION CATALYSTS | MVD, DDT, CDV3 | ACHE 430/4885NFE2L2 596/4885CES2 1328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.