Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930349 | 0.86 | TSHR (0.65) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL6239136 | 0.81 | MEN1 (0.61) | KDM4EMAPK1HIF1ACYP2C19POLB | |
| SCHEMBL16257690 | 0.79 | CYP2C19 (0.36) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL9125881 | 0.79 | — | — | |
| SCHEMBL1524710 | 0.79 | — | — | |
| SCHEMBL6231420 | 0.78 | CASP2 (0.58) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16257775 | 0.78 | ZDHHC20 (0.55) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL3413987 | 0.77 | CYP2C19 (0.41) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL7908937 | 0.77 | CYP2C19 (0.55) | TSHRALDH1A1CYP2C19POLBBLM | |
| SCHEMBL860791 | 0.77 | KDM4E (0.94) | KDM4EMAPK1HIF1ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9908961-B2 | Vinyl alcohol-based graft polymer, method for producing same, and ion-exchange membrane using same | KURARAY CO., LTD. (JP) | 2018-03-06 | — | — | US | disclosed |
| US-5411989-A | Cardiovascular disorders | BOEHRINGER MANNHEIM, GMBH (DE) | 1995-05-02 | — | — | US | disclosed |