Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS1 | Q86VZ5 | 10/20 | 0.83 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.72 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128396 | 0.95 | SGMS1 (0.91) | SGMS1TBXA2RTBXAS1LMNAALDH1A1 | |
| SCHEMBL19392282 | 0.85 | SGMS1 (0.71) | SGMS1LMNAALDH1A1SMN1; SMN2POLB | |
| Sulotroban SCHEMBL34187 | 0.84 | TBXA2R (1.00) | SGMS1TBXA2RTBXAS1ALDH1A1POLB | |
| SCHEMBL9127040 | 0.81 | TBXA2R (0.81) | SGMS1TBXA2RTBXAS1ALDH1A1POLB | |
| SCHEMBL11332922 | 0.81 | TBXA2R (0.81) | SGMS1TBXA2RTBXAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4832368 | 0.81 | POLB (0.67) | SGMS1ALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL9512082 | 0.81 | TBXA2R (0.76) | SGMS1TBXA2RTBXAS1LMNAALDH1A1 | |
| Sulotroban SCHEMBL9585833 | 0.81 | TBXA2R (0.79) | SGMS1TBXA2RTBXAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9850373 | 0.80 | TBXA2R (0.69) | SGMS1TBXA2RTBXAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9850614 | 0.80 | TBXA2R (0.69) | SGMS1TBXA2RTBXAS1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446065-A | Thromboxane antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | disclosed |
| US-4258058-A | Phenoxyalkylcarboxylic acid compounds and thrombocyte-aggregation inhibition | BOEHRINGER MANNHEIM GMBH (DE) | 1981-03-24 | — | — | US | disclosed |