Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.76 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.76 |
| ▸ | SGMS1 | Q86VZ5 | 11/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510829 | 0.87 | SGMS1 (0.64) | TBXA2RTBXAS1SGMS1ALDH1A1LMNA | |
| Sulotroban SCHEMBL34187 | 0.87 | TBXA2R (1.00) | TBXA2RTBXAS1SGMS1ALDH1A1MAPT | |
| SCHEMBL9128396 | 0.84 | SGMS1 (0.91) | TBXA2RTBXAS1SGMS1ALDH1A1MAPT | |
| SCHEMBL9512721 | 0.83 | SGMS1 (0.53) | TBXA2RTBXAS1SGMS1ALDH1A1MAPT | |
| SCHEMBL11332922 | 0.82 | TBXA2R (0.81) | TBXA2RTBXAS1SGMS1ALDH1A1MAPT | |
| SCHEMBL9127040 | 0.82 | TBXA2R (0.81) | TBXA2RTBXAS1SGMS1ALDH1A1MAPT | |
| SCHEMBL9128409 | 0.81 | SGMS1 (0.83) | TBXA2RTBXAS1SGMS1ALDH1A1LMNA | |
| Sulotroban SCHEMBL9585833 | 0.81 | TBXA2R (0.79) | TBXA2RTBXAS1SGMS1ALDH1A1MAPT | |
| SCHEMBL30949337 | 0.81 | SGMS1 (1.00) | TBXA2RTBXAS1SGMS1ALDH1A1HTT | |
| SCHEMBL9850373 | 0.80 | TBXA2R (0.69) | TBXA2RTBXAS1SGMS1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325245-B1 | Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use | TANABE SEIYAKU CO (JP) | 1993-10-20 | — | — | EP | claimed |
| EP-0325245-B1 | Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use | TANABE SEIYAKU CO (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-4258058-A | Phenoxyalkylcarboxylic acid compounds and thrombocyte-aggregation inhibition | BOEHRINGER MANNHEIM GMBH (DE) | 1981-03-24 | — | — | US | disclosed |