Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762024 | 0.81 | KEAP1 (0.44) | CYP1A2KEAP1NFE2L2HPGDPOLB | |
| SCHEMBL8762985 | 0.76 | KEAP1 (0.46) | CYP1A2KEAP1NFE2L2HPGDALDH1A1 | |
| SCHEMBL2788657 | 0.73 | KEAP1 (0.59) | CYP1A2KEAP1NFE2L2POLBNPC1 | |
| SCHEMBL14199593 | 0.71 | GAA (0.39) | CYP1A2HPGDNPC1RAB9AGAA | |
| SCHEMBL402551 | 0.71 | GAA (0.39) | CYP1A2KEAP1NFE2L2HPGDNPC1 | |
| SCHEMBL10941865 | 0.71 | KEAP1 (0.47) | CYP1A2KEAP1NFE2L2HPGDNPC1 | |
| SCHEMBL14300775 | 0.69 | KEAP1 (0.37) | CYP1A2KEAP1NFE2L2HPGDNPC1 | |
| SCHEMBL4081989 | 0.69 | KEAP1 (0.53) | CYP1A2KEAP1NFE2L2POLBCYP3A4 | |
| SCHEMBL6902537 | 0.68 | KEAP1 (0.36) | CYP1A2KEAP1NFE2L2HPGDNPC1 | |
| SCHEMBL28528763 | 0.68 | HPGD (0.50) | HPGDALDH1A1SMN1; SMN2HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5476751-A | Phenylacetates and their use in radiation sensitive compositions | CIBA-GEIGY CORPORATION (US) | 1995-12-19 | — | — | US | disclosed |
| US-5380882-A | Phenylacetates and the use thereof | CIBA-GEIGY CORPORATION (US) | 1995-01-10 | — | — | US | disclosed |