Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762024 | 0.95 | KEAP1 (0.44) | KEAP1NFE2L2HPGDALDH1A1CYP1A2 | |
| SCHEMBL14300775 | 0.78 | KEAP1 (0.37) | KEAP1NFE2L2SLC6A3HPGDALDH1A1 | |
| SCHEMBL9128561 | 0.76 | CYP1A2 (0.42) | KEAP1NFE2L2HPGDALDH1A1CYP1A2 | |
| SCHEMBL6902537 | 0.76 | KEAP1 (0.36) | KEAP1NFE2L2SLC6A3HPGDALDH1A1 | |
| SCHEMBL13785559 | 0.75 | KEAP1 (0.65) | KEAP1NFE2L2ALDH1A1CYP1A2 | |
| SCHEMBL8107590 | 0.71 | ALDH1A1 (0.33) | SLC6A3HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL28512364 | 0.71 | CHRM2 (0.47) | KEAP1NFE2L2HPGDALDH1A1MGLL | |
| SCHEMBL7959308 | 0.70 | SLC6A3 (0.43) | KEAP1NFE2L2SLC6A3ALDH1A1CYP1A2 | |
| SCHEMBL5689417 | 0.70 | SLC6A3 (0.42) | KEAP1NFE2L2SLC6A3 | |
| SCHEMBL14199593 | 0.69 | GAA (0.39) | HPGDCYP1A2GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564405-B1 | Phenylacetic acid esters and their applications | OCG MICROELECTRONIC MATERIALS (US) | 1997-07-16 | — | — | EP | claimed |
| EP-0564405-B1 | Phenylacetic acid esters and their applications | OCG MICROELECTRONIC MATERIALS (US) | 1997-07-16 | — | — | EP | disclosed |