Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095474 | 0.84 | F2 (0.32) | FAAHCA1CA2LMNACYP1A2 | |
| Water SCHEMBL8097685 | 0.83 | F2 (0.31) | FAAHCA1CA2LMNACYP1A2 | |
| SCHEMBL9647534 | 0.82 | ALDH1A1 (0.41) | FAAHCA1CA2LMNACYP1A2 | |
| SCHEMBL8101718 | 0.81 | PARP1 (0.38) | HPGDTSHR | |
| Water SCHEMBL9647014 | 0.80 | PARP1 (0.37) | HPGDTSHR | |
| Hydrochloric Acid SCHEMBL10402148 | 0.80 | PARP1 (0.37) | HPGDTSHR | |
| Hydrochloric Acid SCHEMBL10404503 | 0.79 | PARP1 (0.36) | HPGDTSHR | |
| SCHEMBL10401661 | 0.78 | TSHR (0.42) | CA1CA2CYP1A2HPGDTSHR | |
| SCHEMBL9290481 | 0.77 | KDM4E (0.42) | LMNATSHR | |
| SCHEMBL9518132 | 0.75 | GABRA1 (0.33) | FAAHCA1CA2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385927-A | Hydroxy-3-[1-(1H-imidazol-4-yl)alkyl]-benzenecarboximidamides and their use in treating glaucoma | U C B, S.A. (BE) | 1995-01-31 | — | — | US | disclosed |