SCHEMBL9129155

SCHEMBL9129155

CCCCCCC(OC(=O)c1ccc(OCc2ccccc2)cc1F)C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 1/20 0.45
MAOB P27338 5/20 0.44
MAOA P21397 1/20 0.43
PLA2G2D Q9UNK4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8167025 0.91 MAOB (0.41) MAOBMAOA
SCHEMBL9392171 0.89 KDM4E (0.44) MAOBMAOA
SCHEMBL7167908 0.87 ALDH1A1 (0.57) CTRCMAOBMAOA
SCHEMBL7167903 0.87 ALDH1A1 (0.57) CTRCMAOBMAOA
SCHEMBL9129793 0.85 CTRC (0.51) CTRCMAOB
SCHEMBL9128265 0.85 CTRC (0.51) CTRCMAOB
SCHEMBL7576036 0.85 CTRC (0.51) CTRCMAOB
SCHEMBL6002070 0.85 CTRC (0.51) CTRCMAOB
SCHEMBL8606333 0.85 CTRC (0.51) CTRCMAOB
SCHEMBL8374991 0.84 NPC1 (0.45) CTRCMAOBPLA2G2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5433887-A Liquid crystal compounds SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1995-07-18 US disclosed
US-5110496-A LIQUID CRYSTAL COMPOUND SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1992-05-05 US disclosed
EP-0445037-A2 Liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1991-09-04 EP disclosed