Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4681893 | 0.79 | SLC6A2 (0.53) | SLC6A4SLC6A3SLC6A2TAAR1MAOB | |
| SCHEMBL8664619 | 0.79 | HTR2A (0.54) | SLC6A4SLC6A3SLC6A2TAAR1HTR2A | |
| SCHEMBL6449520 | 0.79 | SLC6A4 (0.60) | SLC6A4SLC6A3SLC6A2TAAR1MAOB | |
| SCHEMBL13003481 | 0.73 | SLC6A2 (0.46) | SLC6A4SLC6A3SLC6A2PPARGPPARA | |
| SCHEMBL19231930 | 0.73 | PPARA (0.49) | SLC6A4SLC6A3SLC6A2PPARGPPARA | |
| SCHEMBL8086703 | 0.72 | MAOA (0.52) | SLC6A4SLC6A3SLC6A2TAAR1HTR2A | |
| SCHEMBL9329236 | 0.72 | MAOA (0.52) | SLC6A4SLC6A3SLC6A2TAAR1HTR2A | |
| SCHEMBL11094964 | 0.72 | MAOA (0.52) | SLC6A4SLC6A3SLC6A2TAAR1HTR2A | |
| SCHEMBL11097972 | 0.72 | MAOA (0.52) | SLC6A4SLC6A3SLC6A2TAAR1HTR2A | |
| SCHEMBL31648185 | 0.72 | SLC6A4 (0.52) | SLC6A4SLC6A3SLC6A2TAAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422355-A | Also for treating memory impairment, dementia or cerebral insufficiency | JOHN WYETH & BROTHER, LIMITED (GB) | 1995-06-06 | — | — | US | disclosed |